Citi Appointed Successor Depositary for Shire plc’s Sponsored Level 2 ADR Program

24 May 2011

Citi (NYSE: C) today announced that its Global Transaction Services business, acting through Citibank N.A., has been appointed by Shire plc, a leading specialty biopharmaceutical company, as the successor depositary bank for its sponsored Level II American Depositary Receipt (ADR) program. Shire’s ADRs trade on the NASDAQ stock market under the symbol 'SHPGY', with each ADR representing 3 ordinary shares. Shire’s ordinary shares are listed on the London Stock Exchange.

Tom Greene, Group Treasurer at Shire, commented: "We are pleased to appoint Citibank as our new ADR depositary and look forward to working closely with them to add continued value both to our existing and potential shareholders in the U.S."

Dirk Jones, Global Head of Securities and Fund Services Client Sales Management at Citi, said: “We are delighted to be appointed depositary bank for Shire’s sponsored ADR program. By leveraging our global equity distribution network and our unique investor relations expertise, we’ll strive to provide outstanding investor access to Shire’s ADR program and bolster its visibility.”

Through its Securities and Fund Services business, Citi’s industry-focused experts provide investors worldwide with tailored solutions delivered through proven global platforms that feature modular, open architecture. With over $13 trillion of assets under custody and the industry's largest proprietary network, clients can leverage Citi's local market expertise and global reach to extract value across the entire investment value chain.

Global Transaction Services, a division of Citi’s Institutional Clients Group, offers integrated cash management, trade, and securities and fund services to multinational corporations, financial institutions and public sector organizations around the world. With a network that spans more than 100 countries, Citigroup’s Global Transaction Services supports over 65,000 clients. As of the first quarter of 2011, it held on average $355 billion in liability balances and over $13 trillion in assets under custody.

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